Beyond BTC and ETH: Top Crypto Investment Picks for 2025 According to Industry Leaders

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When it comes to long-term cryptocurrency investments, Bitcoin (BTC) and Ethereum (ETH) are often the default choices. But what lies beyond these giants? In a recent post on X, prominent crypto influencer @Cobie posed a compelling question: “If you had to invest in a liquid, non-speculative crypto asset for a 3–5 year horizon—and couldn’t choose BTC, ETH, SOL, HYPE, or stablecoins—what would you pick and why?”

The response from key figures across venture capital, trading, and blockchain development was both diverse and insightful. Below, we break down the top picks from industry leaders, analyze their reasoning, and explore the underlying trends shaping the next phase of crypto value creation.


Why Look Beyond Bitcoin and Ethereum?

While BTC and ETH dominate market capitalization and mindshare, the 3–5 year investment horizon demands forward-thinking strategies. As on-chain infrastructure matures, attention is shifting toward assets with real utility, sustainable revenue models, and exposure to emerging narratives like AI integration, privacy resurgence, and decentralized identity.

👉 Discover how leading investors identify high-potential digital assets before they go mainstream.


Top Investment Picks from Crypto Insiders

Jesse Polot-Andrew (Base Lead): Coinbase ($COIN)

Jesse, the driving force behind Base—a rapidly growing Ethereum Layer 2—believes in Coinbase ($COIN) not just as an exchange, but as a foundational player in the crypto ecosystem.

His rationale:

While $COIN is an equity token rather than a native blockchain asset, its position at the intersection of traditional finance and crypto makes it a strategic hedge.


Ansem (Crypto Trader): Worldcoin ($WLD)

Ansem backs Worldcoin ($WLD) as a bet on the future of AI and digital identity.

As artificial intelligence becomes more powerful, distinguishing between humans and bots online will become critical. Worldcoin’s iris-scanning Orb devices aim to create a globally scalable, privacy-preserving method of proving personhood.

Key insights:

This isn’t just about speculation—it’s about preparing for a future where proof of humanity could be more valuable than ever.

👉 Explore platforms enabling secure access to next-gen digital identity systems.


Qw (AllianceDAO Founder): Tokens with Real Revenue

Qw takes a fundamentally different approach: focus only on tokens backed by strong, growing revenue streams.

His view is stark:

“Everything else will go to zero. The era of premium valuation without fundamentals is over.”

He emphasizes that sustainable protocols must generate income through fees, services, or usage—and trade at reasonable valuations relative to that income. This mindset aligns with broader market maturation, where investors increasingly demand transparency and profitability.


Auri (Crypto Trader): Starknet ($STRK)

For those who prioritize scalability, privacy, and Ethereum alignment, Auri champions Starknet ($STRK).

As a zero-knowledge (ZK) rollup on Ethereum:

Potential growth paths:

  1. Become a leading general-purpose L2.
  2. Serve as a Bitcoin L2 if settlement interoperability improves.
  3. Function as backend infrastructure for other chains.

With ZK technology gaining momentum, Starknet could emerge as a core layer in the modular blockchain stack.


Mert (Helius Labs Co-Founder): Jito ($JTO) & Zcash ($ZEC)

Mert splits his conviction between two distinct bets:

Jito ($JTO)

A play on Solana’s continued success. Jito provides liquid staking and MEV optimization on Solana—critical infrastructure for validators and delegators alike. If SOL remains dominant, $JTO captures value directly from network activity.

Zcash ($ZEC)

A resurgence play on privacy coins. With increasing regulatory scrutiny on financial transparency, private transactions may regain relevance. Upcoming technical upgrades under a new research entity could reinvigorate developer interest.

Privacy has always been a cyclical theme in crypto—when trust erodes in centralized systems, demand for anonymity rises.


Alex Svanevik (Nansen CEO): Diversified L1 Portfolio

Rather than betting on one winner, Svanevik advocates for diversification across Layer 1 blockchains.

His portfolio includes:

All assets are staked to generate approximately 4.5% annual yield, blending growth potential with passive income.

This strategy acknowledges uncertainty while maintaining exposure to multiple technological approaches—modular vs. monolithic, Move-based vs. EVM-compatible.


Fishy Catfish (Crypto Analyst): Chainlink ($LINK)

Chainlink stands out due to its entrenched position in real-world asset (RWA) tokenization and cross-chain interoperability.

Why $LINK matters:

As traditional finance integrates blockchain tech, Chainlink acts as the bridge—capturing value not just from data feeds but from compliance, identity, and secure computation.


Murad (Investor): $SPX – The Cultural Meme Movement

$SPX represents something unique: a meme coin with a mission. Inspired by the GameStop saga, it symbolizes resistance against systemic economic inequality—particularly among Gen Z.

It’s not about technology; it’s about cultural momentum, community solidarity, and financial rebellion. In times of job insecurity and societal disillusionment, such tokens can serve as digital safe havens.

While highly speculative, $SPX reflects a growing trend: crypto as social expression.


Awawat (APG Capital): BNB, LEO, AAVE, MKR, XMR

Awawat focuses on survivability and stability over hype.

Selected assets:

His perspective is grounded: many current projects will fail. Only those with solid foundations will survive the next decade.


W3Q: $HOOD & $TSLA – Bridging TradFi and Crypto

W3Q steps outside pure crypto entirely:

He also notes that if self-custody weren’t required, he’d opt for 2x leveraged Bitcoin ETFs, deployed during market bottoms.


Vance Spencer (Framework Ventures): $SKY

Vance highlights $SKY, a lesser-known asset not yet listed on major exchanges. While details are sparse, his pick underscores a VC mindset: early-stage bets on under-the-radar protocols with asymmetric upside.


Arthur (DeFiance Capital): AAVE, ENA, PENDLE, JUP

Arthur spreads exposure across:

This mix balances DeFi fundamentals with next-gen financial primitives.


Frequently Asked Questions

Q: Can non-crypto stocks like $HOOD or $TSLA count as crypto investments?
A: While not native crypto assets, companies deeply integrated into the ecosystem—like Robinhood offering staking or Tesla influencing BTC sentiment—can serve as indirect plays.

Q: Why are privacy coins like Zcash and Monero regaining interest?
A: Growing surveillance concerns and financial censorship fears are reviving demand for anonymous transactions—especially in unstable economies.

Q: Is revenue really the most important factor now?
A: Yes. As markets mature, speculative premiums fade. Protocols generating real cash flow from usage are better positioned for long-term survival.

Q: Should I diversify across multiple L1s?
A: Given technological uncertainty, spreading risk across different architectural approaches (EVM, MoveVM, modular) is prudent.

Q: Are meme coins ever viable long-term holds?
A: Rarely—but culturally significant ones like $SPX may persist due to strong communities and symbolic meaning.

Q: How important is exchange listing for a token’s success?
A: Extremely. Without CEX exposure (like $SKY currently lacks), liquidity and visibility remain limited—critical hurdles for adoption.

👉 Stay ahead of market shifts with tools that track emerging blockchain trends in real time.


The next 3–5 years will reward investors who look beyond narratives and focus on sustainable utility, revenue generation, and macro alignment. Whether through infrastructure plays like Chainlink, privacy revival via Zcash, or cultural movements like $SPX, opportunities abound—for those willing to think critically.