In the ever-evolving world of cryptocurrency, efficiency and scalability are key to maintaining a profitable mining operation. Whether you're focused on Bitcoin, Ethereum, or Litecoin, the hardware you choose can make or break your success. Enter the H110 Pro BTC+, a groundbreaking motherboard engineered specifically for high-performance mining rigs. With support for up to 13 graphics cards, this board redefines what’s possible in a single mining setup.
Designed by ASRock, the H110 Pro BTC+ isn’t just another motherboard—it's a purpose-built solution for serious miners who demand reliability, flexibility, and maximum computational power. Let’s dive into what makes this board a game-changer in the crypto mining landscape.
Unmatched GPU Expansion: 13 PCIe Slots for Maximum Hashrate
The standout feature of the H110 Pro BTC+ is its 14 PCIe slots, allowing for 13 active GPUs to run simultaneously. This level of expansion is unprecedented in consumer-grade motherboards and enables miners to build incredibly dense rigs without needing multiple systems.
More GPUs mean higher hashrates—directly translating to increased mining output across various cryptocurrencies like Ethereum, ZCash, and Monero. Whether you're running a small-scale home rig or managing a large mining farm, consolidating power into a single system reduces complexity, lowers maintenance costs, and improves space efficiency.
👉 Discover how a high-GPU setup can boost your mining returns
Hybrid GPU Support: Mix AMD and NVIDIA Cards
Flexibility is crucial when sourcing graphics cards in today’s volatile market. The H110 Pro BTC+ supports hybrid configurations, meaning you can mix and match AMD and NVIDIA GPUs within the same rig.
This capability allows miners to adapt to availability and pricing fluctuations without being locked into a single brand. For example, you could run 8 AMD cards and 5 NVIDIA cards together under Windows 10 using mining software like GUIMiner—no complex configurations required. Simply install the drivers, launch your preferred miner, and start hashing.
Such versatility ensures that your mining operation remains agile and cost-effective, regardless of supply chain constraints or market shifts.
Optimized for 24/7 Operation: Stability You Can Trust
Mining isn’t a part-time job—it runs around the clock. That’s why system stability is non-negotiable. The H110 Pro BTC+ is built from the ground up for continuous operation, featuring:
- 8-phase digital CPU power design for clean, efficient power delivery
- 2-ounce copper PCB to enhance heat dissipation and signal integrity
- Intel® Ethernet controller for reliable network connectivity
These components work together to ensure your rig stays online, stable, and performing at peak levels—even under sustained load. Overheating and power instability are two of the biggest threats to mining uptime, and this board addresses both with industrial-grade engineering.
Additionally, onboard power and reset buttons provide easy physical access for troubleshooting or restarting the system without needing a connected keyboard or monitor—ideal for headless mining environments.
Seamless Integration with ethOS and Windows
The H110 Pro BTC+ is compatible with both specialized mining operating systems and mainstream platforms:
Running on ethOS (Linux-Based)
ethOS is a popular Linux-based distribution tailored for GPU mining. After extensive compatibility testing, ASRock confirmed that the H110 Pro BTC+ supports 13 AMD GPUs seamlessly under ethOS. The OS handles driver optimization, fan control, and remote monitoring out of the box, making it perfect for large-scale deployments.
ethOS also supports multiple cryptocurrencies beyond Ethereum, including:
- ZCash (ZEC)
- Monero (XMR)
- Ravencoin (RVN)
- Ergo (ERG)
Its lightweight nature and automated management tools reduce overhead and simplify fleet operations.
Running on Windows 10
For users less familiar with Linux, the board fully supports Windows 10, allowing hybrid GPU setups using tools like GUIMiner or other Windows-compatible mining software. This lowers the entry barrier for beginners while still delivering professional-grade performance.
👉 Learn how to optimize your mining OS for better efficiency
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These terms reflect common queries from miners researching scalable, reliable hardware solutions.
Frequently Asked Questions (FAQ)
Q: Can I really run 13 GPUs on one motherboard?
Yes. The H110 Pro BTC+ has 14 PCIe slots, supporting up to 13 graphics cards simultaneously. This configuration is ideal for maximizing hashrate in a single system.
Q: Does it support both AMD and NVIDIA GPUs at the same time?
Absolutely. You can mix AMD and NVIDIA cards—for example, 8 AMD and 5 NVIDIA—in hybrid mode when using Windows 10 with compatible mining software.
Q: Is the motherboard compatible with ethOS?
Yes. It has been tested and verified to support up to 13 AMD GPUs under the ethOS Linux distribution, making it ideal for professional mining farms.
Q: What power supply do I need for a full 13-GPU setup?
A high-wattage, modular PSU (or multiple PSUs) with sufficient PCIe power connectors is required—typically 1600W or higher depending on GPU models. Proper power distribution and cabling are critical.
Q: Why is the 2-ounce copper PCB important?
Thicker copper layers improve thermal conductivity and reduce electrical resistance, helping maintain stable performance during prolonged mining sessions.
Q: Can I remotely manage my mining rig with this motherboard?
Yes. When paired with ethOS or Windows-based remote desktop tools, you can monitor temperatures, adjust fan speeds, update software, and restart the system from anywhere.
Final Thoughts: A New Benchmark in Mining Hardware
The H110 Pro BTC+ sets a new standard for what a mining-focused motherboard should offer: massive GPU scalability, hybrid compatibility, enterprise-level stability, and seamless OS integration. Whether you're upgrading an existing rig or building a new mining farm from scratch, this board delivers the foundation you need for long-term profitability.
As cryptocurrency mining continues to grow more competitive, having an edge in hardware efficiency can be the difference between profit and loss. The H110 Pro BTC+ gives miners that edge—powering dense, reliable, and future-ready systems capable of handling tomorrow’s challenges today.
👉 Start building your next-gen mining rig with optimized performance tools